In recent decades, many researchers throughout the scientific world have focused their studies on gene therapy. Gene therapy involves the insertion of healthy genes in the body of a patient to compensate for the loss of functionality of altered genes that are responsible for a disease, with the purpose of restoring the proper function of genes, and thus halting the disease. This approach is...read
Hypertension is a major public health problem: in Italy there are 15 million people suffering from hypertension, and the need to treat is of increasingly greater importance.
Treatment of hypertension is based on two approaches: pharmacological and non
pharmacological. The latter, which is of great importance for avoiding lifelong use of drugs, is based on smoke avoidance, weight loss and...read
Loss of fertility is one of the most frequent consequences for patients undergoing treatments with chemotherapy and/or radiation for cancer. When the disease occurs at young age, that is when the patient has not yet achieved his or her desire for maternity or paternity, the inability to have biological children may cause great sense of deprivation and frustration.
Just recently the news...read
Phosphatidylcholine is a phospholipid able to dissolve the fat with which it comes into contact. The substance has been used for years in the treatment of hypercholesterolemia, and only recently found an important role in the cosmetic field. To date the most effective solution for localized fat and cellulite was offered by liposculpture, a surgical technique that provides for the aspiration of...read
Beautiful days are starting, and dramatically you realize that summer is near, and it is time to take countermeasures: crazy diets, endless sessions in the gym, massages, and purchase of tons of miracle creams. The truth is that, in reality, the right time to start the “bikini test” program for the following year is the very same day you return from summer vacation.
This is the theory, hard...read
This condition, which is very common in general medical practice, presents itself with symptoms characterized by local discomfort along the course of the vessel involved: redness is the other feature.
Many studies have been conducted in regard to the modalities of treatment of superficial venous thrombosis, to understand their real effectiveness: it is not clear whether localization and...read
The term "halitosis" is a condition in which malodorous air is emanated during respiration. It can affect persons of all ages and have different causes.
In reality, what is commonly considered a problem of purely social nature, is instead a complex phenomenon that must be distinguished according to the cause that produces it.
The causes of this disorder may be of oral origin (dental, lingual,...read
What's the hardest thing in taking care of people suffering from diabetes? Many doctors would answer that the greatest problem is that patients with diabetes not always do what they say they do: they often do not follow the diet and physical activity programs, they do not control their blood sugar, and, maybe, they do not take the prescribed medicines. Results? Complications of diabetes,...read
Many biological functions are exercised according to daily rhythms (1). Modifications of these rhythms are present in all the affective disorders (2, 3, 4), as also indicated in the Diagnostic Statistical Manual of Mental Disorders (DSM IV Items) (5). Therapies of proven effectiveness act directly changing circadian rhythms and mainly include the Light Therapy and Sleep Deprivation; drug...read
Nausea and vomiting caused by chemotherapy are among the most frequent and worst tolerated side effects of anti-cancer treatments. The evidence of the prognostic significance of the dose intensity and dose dense led researchers to develop increasingly aggressive chemotherapy schemes with ever higher doses of drugs. Vomiting is disabling and, along with alopecia, is among the most poorly tolerated...read
At present, excess weight and obesity are issues for which a unique causative factor and a mechanism that supports them have not been clearly understood. For this reason the treatment of obesity is not based on a rational, but instead relies almost exclusively on a strictly empirical basis.
In this case, help can be found in the Traditional Chinese Medicine (TCM) and in Homeopathic Medicine,...read
Carboxitherapy consists in the therapeutic use of carbon dioxide gas administered subcutaneously. The Carboxitherapy finds applications in various fields: vascular, medical aesthetics, dermatology and plastic-surgery. Recent this therapy has been used to treat skin aging and to improve the elasticity of tissues. What is carbon dioxide? CO2 is an odorless and colorless gas, and together with...read
Modern studies on wine date back to 1854, year in which Prof. Mulder, of the University of Utrecht, Netherlands, published a book titled “ The chemistry of wine”, where he identified primary salts, acids and minerals that are dissolved in wine. Later, the introduction of chromatography, shifted the focus to Anthocyanins, which opened a new dimension in the study of the relationship between...read
DISCUSSION Compliance with the diet is critical to achieving and maintaining a good result, and is based on several factors; the choice of a diet very close to the habits of patients and the whole family, can lead to greater diet adherence over time. It is also important not to underestimate the interval of time between meals which is about 7 hours in the lifestyles of our population. herefore,...read
DISCUSSION Compliance with the diet is critical to achieving and maintaining a good result, and is based on several factors; the choice of a diet very close to the habits of patients and the whole family, can lead to greater diet adherence over time. It is also important not to underestimate the interval of time between meals which is about 7 hours in the lifestyles of our population. herefore,...read
Colitis is an inflammation of the mucosa of the colon due to many causes. Commonly, we use the term colitis to define sporadic episodes of diarrhea accompanied by abdominal pain. We shall focus our attention on spastic colitis, which is characterized by recurring episodes not related to biochemical and organic abnormalities of the colon: more appropriately we will talk about the irritable colon...read
INSULIN DETEMIR: a modern concept of basal insulinization
The main objective of insulin therapy in diabetic patients is the maintenance of a nearly normal blood glucose level. The introduction of fast-acting insulin analogs (Aspart, Lispro and Glulisine) in the treatment of diabetes mellitus, has resulted in improved control of postprandial blood glucose with lower risk of hypoglycemia after...read
Introduction
The management of SCLC has been recently improved and survival rates are 15-25% at 2 years among patients with limited stage and 0-3% among those with extensive disease. The median overall survival with the combination chemotherapy is 14 to 16 months for patients with limited disease and 8 to 11 months for those with extensive disease. Most controlled clinical trials of SCLC define...read
Actresses, singers, journalists, politicians and top models: the problems of poor venous circulation in the legs can strike anyone without exceptions.
At the end of the day, especially when you spend long hours standing, it is normal to experience swelling and heaviness in the legs, and to note the presence of unsightly capillaries, which in many cases show up around the ankles and the back of...read
Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.
A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and...read
Aim: The aim of my study has been to evaluate the efficacy of a new method of compression sclerotherapy of GSV and SSF.
Materials and Methods: 180 lower extremities with primary varicous veins, with a long reflux of the GSV (C2-6, Ep, As2 p, Pr), have been submitted to sclerotherapy applying the following method: injection of the trunk of the GSV, according to Sigg's technique; echoguided...read
Aim: The aim of my study has been to evaluate the efficacy of a new method of compression sclerotherapy of GSV and SSF.
Materials and Methods: 180 lower extremities with primary varicous veins, with a long reflux of the GSV (C2-6, Ep, As2 p, Pr), have been submitted to sclerotherapy applying the following method: injection of the trunk of the GSV, according to Sigg's technique; echoguided...read
The use of psychotropic drugs in children has long been a subject of debate in the medical field, particularly regarding the use of SSRI(Selective Serotonin Reuptake Inhibitors) antidepressants, considering that they could increase the risk and suicidal behavior.
The FDA in USA has compiled a study covering all the risks due to the utilization of this class of drugs: despite the wariness,the...read
The management oral anticoagulant therapy (OAT) is of great importance for family doctors, because there are many people with venous thromboembolism, or various cardiovascular diseases, such as myocardial infarction and stroke, who are at great risk for embolism.
Oral anticoagulant therapy (OAT), is designed to depress in a controlled and reversible manner blood coagulability, which is measured...read
Gene Src (short for sarcoma) is part of a family of proto-oncogenic tyrosine kinases active in many tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.
A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and...read
Gene Src (short for sarcoma) is part of a family of proto-oncogenic tyrosine kinases active in many tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.
A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and...read


