TAGS cancer
2008-11-20

Women with gynecological cancers must be treated in hospital centers of excellence, otherwise the risk of being subjected to sub-optimal treatments can significantly result in a negative effect on the outcome. This is confirmed by a recent search of the National Institute of Tumors in Milan which took into account a significant sample of 500 patients treated at the center of Milan after having...
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2008-11-20
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The tumor suppressor gene pRb2/p130 may provide the first independent prognostic biomarker in cases of soft tissue sarcoma (STS), according to an international collaboration of researchers, including scientists at the Sbarro Institute for Cancer Research and Molecular Medicine at the College of Science and Technology at Temple University in Philadelphia, PA, the Department of Human Pathology and...
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2009-01-21

Pain is an "epidemic" that hinders the full expression of life to millions of people, both in European countries and, even more, in the Mediterranean countries with lesser health-power. The World Health Organization indicates that pain is one of the main causes for which medical attention is requested, and represents a serious public health problem (1-3).
Defeating pain therefore allows people...
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2009-02-20

Chromium (Cr) is a transition element that exhibits three possible states: metallic stable, trivalent and hexavalent. While the trivalent form is characterized by a relatively low toxicity and is considered an essential nutrient, hexavalent chromium, present in several compounds of industrial origin (including chrome and thiols), is considered highly toxic, and on the basis of experimental and...
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2009-02-20

Introduction
The management of SCLC has been recently improved and survival rates are 15-25% at 2 years among patients with limited stage and 0-3% among those with extensive disease. The median overall survival with the combination chemotherapy is 14 to 16 months for patients with limited disease and 8 to 11 months for those with extensive disease. Most controlled clinical trials of SCLC define...
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2009-04-08

(March 22, 2009 – Philadelphia, PA) -- The clinically approved AIDS drug ABC (Abacavir) can reduce proliferation and induce differentiation of human medulloblastoma cells through the downregulation of telomerase activity, which may make it an effective therapeutic strategy for the treatment of the highly malignant primary brain tumors, according to research published in the International...
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2009-05-19

Hematuria is a symptom that, when present, triggers a series of diagnostic assumptions requiring a number of important investigations to clarify its origin.
The first task is to get a description of the urine color: there is a significant difference between orange-red, brown-red, or bright red.
The medical history and the physical examination are very important, while the “the three...
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2010-04-27

Gene Src (short for sarcoma) is part of a family of proto-oncogenic tyrosine kinases active in many tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.
A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and...
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2010-06-07

Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.
A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and...
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2010-06-23

Colorectal tumors are the second leading cause of cancer death in the United States and represent a major threat in Italy, but, fortunately, good screening can yield a survival of 90 percent for cancer of the colon, and 80 percent for cancer of the rectum.
All this is possible, and starts with a good conversation between the patient and the general practitioner, who more than anyone else...
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2010-07-09

The Institute of Biosciences for Human Health of the Human Health Foundation Onlus of Spoleto (HHF), Foundation for Human Health, based in Spoleto and Terni, opened in Terni, in the Maratta location (via Bartocci 9 / B) on June 7.
Some years ago, two professionals coming from completely different areas of work, met and discussed at length, and afterwards created, a completely innovative project...
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2010-09-23

If there is a clear need to think and work in innovative ways to deliver health services that achieve high quality, it is equally true and that we should develop a better and more appropriate investment model, in order to avoid losing resources in processes that will not give any certainty that the arrangements already in place will change.
We believe that now there is an opportunity for...
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2010-10-08

On Saturday, October 2, at the Conference Center of Hotel Fior di Castelfrancoveneto, the second day of the seminar entitled: "Integrated diagnostic and therapeutic approach: hepatocellular carcinoma, GIST, renal cancer, neuroendocrine tumors”.
Session I on Hepatocarcinoma was introduced by the President of the Congress, Prof. Paul Manente who, at the start, wished to remember the famous...
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2010-10-15

Until recently, vascularization of malignant tumors was considered the exclusive result of
directed capillary in-growth. However, recent advances have been made in identifying the
processes involved in vascular remodelling like as vasculogecin mimicry (for a review read
reference 1).
Vasculogenic mimicry was first described by the unique ability of aggressive
melanoma cells to express an...
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2010-10-21

In 1976 Harold zur Hausen published in the prestigious Cancer Research Journal a scientific paper that indicated the possible relationship between the Human Papilloma Virus and the development of uterine cervical cancer. It inaugurated a new branch of research over the years has led to important results which link HPV to several types of cancers, such as squamous cell skin cancer, anal cancer,...
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2010-10-28

Alarm in Naples. The City is re-submerged by trash. Heaps of garbage prevents access to stores and night bonfires are a dramatic spectacle. Naples is burning, and the pictures of this sad and shameful spectacle go again around the world after a little more than a year since the last emergency.
The issue involves the health of citizens and cannot be hushed up. For several decades there has been a...
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2010-11-02

On October 15 and 16, 2010, the VII "Wine and Health" Conference was held in Montalcino at the Theatre of the Astrusi
The event, sponsored by the Wine and Health Association in collaboration with the Municipality of Montalcino and the Consorzio del Vino Brunello, addressed this important and timely issue: the wine and its health effects. The Mayor of Montalcino Maurizio Buffi, the President of...
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2010-11-08

COPD is no longer a standalone condition, rather is a disease that is too often linked with other diseases, including various non-respiratory disorders, such as cardiovascular disease, cancers and even osteoporosis, which, in turn, are all diseases associated to other chronic conditions, such as hypertension and arterial disease.
The statistics, moreover, are clear: over half of the people...
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2010-12-10

Dr. Franklin Garcia, Chancellor 0f the Universidad Autonoma de Santo Domingo, which is one of the biggest Universities of the Americas for its size, history and curriculum, presented to Professor Antonio Giordano, director of the Sbarro Institute in Philadelphia, the title of Professor Emeritus. The following is the translation of the Chancellor’s speech:
"The delivery of the title of...
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2010-12-15

Journalist Tony Kirby, in an article published in the famous journal “The Lancet”,wrote:
"Even though Canada does not expose its citizens to asbestos, it plans to continue exporting this deadly substance to the developing countries, drawing widespread condemnation “.
Professor Antonio Giordano, director of the Sbarro Institute for Cancer Research, Philadelphia, USA, is one of the...
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2011-02-28

(February 24) – PHILADELPHIA -- Despite innumerable studies on lung cancer, many aspects of the disease have yet to be understood, including the role played by the retinoblastoma-related protein Rb2/p130 in the evolution of the disease. In a new study, researchers from the Sbarro Health Research Organization Center for Biotechnology Research (SHRO), a cancer, cardiovascular and diabetes...
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2011-03-30

Seven prestigious Italian-Americans, who have excelled in the fields of communication, business and medicine, were elected to the Board of Directors of the National Italian American Foundation's (NIAF) last March 11, 2011, during a meeting at the Wigwam Golf Resort & Spa in Litchfield Park, Arizona.
The new NIAF "Board of Directors" elected members are: Maria Bartiromo, the CNBC network...
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2011-04-11

In Campania breast cancers were up twenty percent in women under age 40, according to the data presented by Professor Antonio Giordano, president of the Scientific Board of Crom Mercogliano, who has been conducting this study in collaboration with the Human Health Foundation of Spoleto, but especially with the United States.
In Campania the monitoring was made possible through collaboration with...
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2011-04-15

Help cancer and cardiovascular diseases research, and work with us to brin our brains back from foreign countries.
Please, give your 5x1000 to Human Health Foundation Onlus.
Tax Identification Code 02896450547
Sign up for the support of non-profit Social Organizations and support our Institute of Biosciences for Human Health of Terni.Together we can do a lot.
To better know us go to:...
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2011-05-24

The meeting aims to provide an overview of recent developments in translational cancer research. In particular the mechanisms of cell cycle control as a platform for the identification of molecules designed to inhibit cell proliferation in cancer cells will be discussed; more specifically, will discuss the potential anticancer effects of some agents that act as inhibitors of histone...
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2011-06-06

The "Human Health Foundation Onlus" which is based in Spoleto, is a non-profit Foundation for Basic and Translational Scientific Research; scientific personalities from different countries, both European and International, are members of the Foundation.
The Foundation is purely a not-for-profit research organization, regardless of its legal status or funding source, whose principal statutory...
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2011-06-13

A few days ago, the FDA (Food and Drug Administration, the American institution that controls food and drug safety) approved the use of Ipilimumab, a drug based on a monoclonal antibody, which has yielded encouraging results in the fight against melanoma.
During the testing phase of this antibody, the survival of patients has increased significantly: it has almost doubled at one year, rising...
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2011-07-01

While many young people mistakenly believe that hand-rolled cigarettes are less dangerous to smoke than filtered cigarettes, a new study shows that smoking hand-rolled cigarettes has stronger genotoxic and oxidative effects on the metabolism than smoking manufactured filtered-cigarettes. The research was published in the journal Mutation Research.
Cigarette smoking is a major cause of human...
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2011-08-02

How long can Naples resist with the trash in the street, before the health care alarm becomes a real epidemic? Giulio Tarro, a leading expert in virology at the international level, a student of the "Monument" of medicine at Albert Sabin, director emeritus at Cotugno Hospital from 1973 to 2006, and Adjunct Professor at the Department of Biology, Center for Biotechnology, Sbarro Institute for...
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2011-09-26

A new study shows that there are major differences between oncologists and primary care physicians regarding knowledge, attitudes, and practices required to care for American's 12 million cancer survivors. That is the key finding of the first nationally representative survey of doctors that reveals how these differences pose significant barriers to effective communication and coordination of care...
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2011-09-28

A fundamental problem in cancer research is identifying the cell type that is capable of
sustaining neoplastic growth. There is evidence that the majority of cancer cells are
clones and that cancer cells represent the progeny of a single cell (reviewed in [1] La
Porta 2009). However it is unclear which cells possess the tumor-initiating cell function,
maintaining the tumor growth. The idea of...
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2011-09-08

Chromoendoscopy associated with high-definition video endoscopy offers the possibility to analyze the spectra of colors in the captured image, using dyes (indigo carmine, methylene blue), and high-definition zooming, to study the mucosa (magnification). This technique becomes essential for the recognition of early stages of dysplasia and intestinal cancers, but becomes crucial in patients at high...
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2012-01-25

Gary Stein, graduate of the University of Vermont is returning home as co-Director of the Vermont Cancer Center and Chair of the Department of Biochemistry. Following graduate training at UVM in physiology and biology and post-graduate training in pathology, Gary joined the faculty at the University Of Florida College Of Medicine where he became Vice-Chair of the Department of Biochemistry. In...
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2012-03-23

A healthy diet, which is rich in fruits and vegetables, whole grains and legumes and contains limited red meat, preserved meats and sugared beverages, protects against tumor development and recurrences.
The right diet can be one “protective” factor against cancer, but lifestyle must always be considered as well. Indeed, it is important to engage in physical activity and avoid alcohol and...
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2012-04-27

Inactivation of the retinoblastoma tumor suppressor protein (pRb) by phosphorylation triggers uncontrolled cell proliferation. Accordingly, activation of cyclin-dependent kinase (CDK)/cyclin complexes or downregulation of CDK inhibitors appears as a common event in human cancer.
Now, a new study from the Sbarro Health Research Organization shows that Pin1 (protein interacting with NIMA (never...
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